- Sandra Bullock was given the first-ever Favorite Humanitarian award for her efforts at a New Orleans high school.
- Christina Aguilera picked up a People's Voice award after her performance of "Blank Page." Alicia Keys performed a mash-up of "Girl on Fire" and "New Day.” Jason Aldean did "My Kinda Party."
- The boy band battles saw The Wanted beat One Direction for Favorite Breakout Artist. One D took home Favorite Song for "What Makes You Beautiful" and Favorite Album for Up All Night.
- Ellen Pompeo took home Favorite Dramatic TV Actress. Her show Grey's Anatomy was the Favorite TV Drama.
- Nathan Fillion nabbed Favorite Dramatic TV Actor. His series Castle was named the Favorite TV Crime Drama.
- Glee’s Lea Michele and Chris Colfer won respective Favorite Comedic TV Actress and Actor.
- Host Kaley Cuoco kicked off the night learning how to be a "kick-butt" host with help from LL Cool J and some of the Twilight gang. She closed the night accepting a win for Network TV Comedy with her Big Bang Theory cast-mates.
Movie: The Hunger Games
Movie Actor: Robert Downey Jr.
Movie Actress: Jennifer Lawrence
Action Movie: The Hunger Games
Action Movie Star: Chris Hemsworth
Face of Heroism: Jennifer Lawrence, The Hunger Games
Comedic Movie: Ted
Comedic Movie Actor: Adam Sandler
Comedic Movie Actress: Jennifer Aniston
Dramatic Movie: The Perks of Being a Wallflower
Dramatic Movie Actor: Zac Efron
Dramatic Movie Actress: Emma Watson
Movie Franchise: The Hunger Games
Movie Superhero: Robert Downey Jr. as Iron Man
On-screen Chemistry: Jennifer Lawrence, Josh Hutcherson and Liam Hemsworth in The Hunger Games
Movie Icon: Meryl Streep
Favorite Humanitarian: Sandra Bullock
SCRIPTED TV WINNERS
Network TV Comedy: The Big Bang Theory
Network TV Drama: Grey's Anatomy
Cable TV Comedy: Awkward
Cable TV Drama: Leverage
Premium Cable TV show: True Blood
TV Crime Drama: Castle
Sci-fi/fantasy TV show: Supernatural
Comedic TV Actor: Chris Colfer
Comedic TV Actress: Lea Michele
Dramatic TV Actor: Nathan Fillion
Dramatic TV Actress: Ellen Pompeo
UNSCRIPTED TV WINNERS
Daytime TV host: Ellen DeGeneres
Late-night Talk Show Host: Jimmy Fallon
New Talk Show Host: Steve Harvey
Competition TV Show: The X-Factor
Celebrity Judge: Demi Lovato
Male Artist: Jason Mraz
Female Artist: Katy Perry
Pop Artist: Katy Perry
Hip-hop Artist: Nicki Minaj
R&B Artist: Rihanna
Band: Maroon 5
Country Artist: Taylor Swift
Breakout Artists: The Wanted
Song: One Direction, “What Makes You Beautiful”
Album: One Direction, Up All Night
Music video: Katy Perry, “Part of Me”
People's Voice: Christina Aguilera